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This contains food. While Viagra could be taken with a meal, grapefruit or grapefruit juice must be avoided. Sildenafil could cause painful erections, so it is mostly prevented in men with penile deformities (Peyronie’s disease, cavernosal fibrosis, or angulation) or other conditions that increase the danger for priapism such as sickle cell anemia, leukemia, or a number of myeloma. While Viagra will be taken with meals, grapefruit and grapefruit juice ought to be avoided on the day a dose is taken. Grapefruit has substances that decelerate the breakdown of sildenafil in the physique, raising the danger of unwanted side effects, together with some of the worst uncomfortable side effects. Grapefruit has substances that block the liver enzyme that breaks down sildenafil, elevating the danger of unintended effects. Because sildenafil is damaged down by the liver and excreted within the urine, people with severe kidney disease or liver issues may should be monitored or have doses decreased. |
